Volume - 3

Original Research

Non-Acetylated Hemicellulose-Based Hydrogel Preparation for Sustained and Targeted Delivery of Drugs


by -Samit Kumar*, Riya Khilwani and Kamlesh Choure

Author's Affiliation: Department of Chemistry, AKS University, Sherganj Road, Satna- 485001 (M.P) India

Published: 20-Jun-2020

DOI: 10.51323/JIAR.3.1.2020.1-7

Views: 50

Pages: 1-7

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Abstract

Hydrogels are water-swollen, three-dimensional, cross-linked polymeric network produced by simple reaction of one or more monomers with the ability to swell in an aqueous medium. Consequently, hemicellulose-based hydrogels were prepared by the combination of hemicellulose (HC) and acrylic acid (AAc) in different ratios. Result showed that the hydrogels absorbed up to 300% of water when it is prepared by combining HC and AAc in the ratio of 1:8. This combination ratio was preferred as a suitable candidate for drug loading and release profile in near future. The prepared hydrogel may be used in the biomedical field for sustained and targeted release of drugs.

Keywords

Hydrogels, Hemicellulose, Acrylic Acid