NON-ACETYLATED HEMICELLULOSE-BASED HYDROGEL PREPARATION FOR SUSTAINED AND TARGETED DELIVERY OF DRUGS

Category: Previous Issue Created: Tuesday, 24 January 2017 Published: Tuesday, 24 January 2017 Written by Samit Kumar,Riya Khilwani and Kamlesh Choure

Department of Chemistry, Faculty of Basic Science, AKS University, Sherganj Road, Satna- 485001 (M.P) India 

Department of Biotechnology, Faculty of Life Science and Technology, AKS University, Sherganj Road, Satna- 485001 (M.P) India

*Corresponding author : Samit Kumar*, Riya Khilwani and Kamlesh Choure

*Corresponding Author: E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Hydrogels are water-swollen, three-dimensional, cross-linked polymeric network produced by simple reaction of one or more monomers with the ability to swell in an aqueous medium. Consequently, hemicellulose-based hydrogels were prepared by the combination of hemicellulose (HC) and acrylic acid (AAc) in different ratios. Result showed that the hydrogels absorbed up to 300% of water when it is prepared by combining HC and AAc in the ratio of 1:8. This combination ratio was preferred as a suitable candidate for drug loading and release profile in near future. The prepared hydrogel may be used in the biomedical field for sustained and targeted release of drugs.

 

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